Uterine fibroids

About this activity

Leiomyomas of the uterus (or uterine fibroids) are benign tumors that arise from the overgrowth of smooth muscle and connective tissue in the uterus. Histologically, a monoclonal proliferation of smooth muscle cells occurs. A genetic predisposition to leiomyoma growth exists. Uterine leiomyomas (fibroids) are the most common benign gynecologic tumors. They primarily affect women of reproductive age, and the estimated incidence of fibroids is over 70% by 50 years of age.[1, 2, 3, 4, 5]