Seroprevalence and characterisation of herpes simplex virus from human immunodeficiency virus in samples collected from two provinces in South Africa: a retrospective study

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Herpes simplex virus (HSV) is a prevalent organism that belongs to the sub-family of alpha Herpesviridae (. The prevalence of HSV-1 and HSV-2 infection in the United States from a survey conducted in 2018 was reported as 47.8% and 11.9%, respectively (. Recently, HSV-1 has become a major factor influencing genital herpes in most industrialised nations with about 140 million people, aged 15–49 years, infected with genital HSV-1 (. According to. It is apparent that a well-built interaction exists between HSV-2 and HIV-1 infection (. The focus of this study was to establish the prevalence of HSV antibodies and HSV-DNA in HIV-1 sera collected from National Health Laboratory Service (NHLS) laboratories. In addition, HSV-2 and HIV-1 co-infections were examined in the samples.