Molecular docking analysis of selected phytochemicals on two SARS-CoV-2 targets

About this activity

Since 2003, three coronaviruses have been associated with pneumonia, the first was severe acute respiratory syndrome coronavirus (SARS-CoV-1). The entry into the host cell by the coronaviruses is usually mediated by the spike (S) glycoprotein. Possibly, potent inhibitors of these two targets will be able to interfere with the SARS-CoV-2 replication process and thus serves as potential drugs for the management of the COVID-19. Hence, this work is aimed at identifying some potential lead compounds of plant origin that can serve as candidates for testing against the SARS-CoV-2 virus.