Wood-decaying fungi found in Southern Ghana: A potential source of new anti-infective compounds

About this activity

Several plants and fungi have served as sources of many drugs that are used in clinics. A proportion of microbial pathogens that afflict mammals may possibly infect fungal species, since they are both eukaryotes with related cellular metabolism. Unlike mammals, fungi have a higher tendency to produce relevant chemical compounds for combating infectious pathogens. Therefore, exploring fungal secondary metabolites to identify suitable candidates which can be developed as novel antibiotics is not only timely but also urgent. Thus, our global public health settings can benefit immensely from the defense strategies used by fungi against pathogenic microorganisms such as. Wood-decaying fungi (WDF) belong to the phylum Basidiomycetes; they constitute the major group of fungi responsible for degradation of organic matter. This study investigated the potential of indigenous WDF found in Ghana to produce antimicrobial compounds. This objective was achieved by collecting diverse WDF from differen...