Cost-effectiveness of once-daily versus twice-daily regimens in the treatment of HIV infection in sub-Saharan Africa: a probabilistic decision model

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Sub-Saharan Africa (SSA) is the region most heavily affected by human immunodeficiency virus (HIV). While the literature has focused on the effectiveness of QD versus twice a day (BID) regimensn Objectives Course Objective Regimen simplification of ART, by administering them less frequently, has been suggested as a practical approach to improve adherence. The aim of this study was to assess the cost-utility of once-daily (QD) versus twice-daily (BID) antiretroviral (ART) regimens in the treatment of HIV. n